Gene Expression Omnibus Analysis with Shiny (GEO-AWS)
[Team Project] [Private] Gene expression is the process within a cell by which a sequence of DNA is transcribed into RNA and the RNA is then translated into a protein. The collection of proteins within a cell determines its physical structure and characteristics, including whether or not the cell is healthy or becomes cancerous. The Gene Expression Omnibus (GEO) publicly archives and freely distributes forms of functional genomic data submitted by the scientific community. However, GEO has limited tools that study and analyze data for researchers. Shiny is a web application framework for R. Using Shiny, we are developing a tool that provides a simple graphical user interface for pulling information from GEO so that a user can conduct an in-depth analysis on the gene expression profiles of interest. Specifically, a user can study genetic expressions and clinical data together with graphical summary and analysis. With this tool, researchers are able to efficiently identify specific gene that may respond to certain diseases.